New York Heart Association Functional Class correlated with Depression: Study in Saiful Anwar Hospital
DOI:
https://doi.org/10.21776/ub.hsj.2021.002.03.5Keywords:
NYHA Class, Heart Failure, Montgomery-Asberg Depression Rating Sclae (MADRS), DepressionAbstract
Background:Â Heart Failure prevalence was raising as one of the mostÂ
Objective: to find the correlation of New York Heart Association Functional Class in heart failure patient with Depression
Method:Â This cross-sectional study recruited 342 patients diagnosed with HF with previously for more than 3 months, at dr. Saiful Anwar General Hospital during December 2016 to March 2021. Each patient was interviewed for their demography data, and their clinical data, and assessed for their depression with Montgomery-Asberg Depression Rating Scale for Indonesian version. We used Spearman coefficients (rs) to evaluate the correlations between variables.
Results: Baseline characteristic among depression and non-depression group demonstrated no significant difference (p>0.05), but for marital status. Populations was predominantly male, with ACE-i/ARB and Beta-blockers treatment. Non predominant treatment was MRAs, Diuretics, Digoxin. Baseline age was 22 years old until 87 years old. Baseline LVEF was 50.4±12.9%. (p >0.05). There were significant correlations between NYHA Class and marital status (p < 0.05), while the other baseline was not significantly different. We performed log regression for the confounding. The result was NYHA Class significantly correlated with and effects the depression.
Conclusion: In heart failure patients, NYHA Class was significantly correlated with depression.
Keyword: NYHA Class; Heart Failure, Montgomery-Asberg Depression Rating Sclae (MADRS), Depression
References
World Health Organization. Cardiovascular diseases. Geneva: World Health Organization; 2017. Retrieved from, http://www.who.int/mediacentre/ factsheets/fs317/en/. [Accessed 21 March 2020]. (WHO, 2017)
Heron M. Centers for Disease Control and Prevention. 2019. Deaths: Leading Causes for 2017. National Vital Statistics Reports, Vol. 68, No. 6, June 24, 2019 (Heron, 2019)
P2PTM Kemenkes RI. Hari Jantung Sedunia (HJS) Tahun 2019 : Jantung Sehat, SDM Unggul. http://p2ptm.kemkes.go.id/kegiatan-p2ptm/pusat-/hari-jantung-sedunia-hjs-tahun-2019-jantung-sehat-sdm-unggul. [Accessed 29 January 2021]. (P2PTM Kemenkes RI, 2019)
Januzzi JL, Mann DL. 2019. Approach to the Patient with Heart Failure in Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine, Eleventh Edition. Philadelphia: Elsevier.
Celano CM, et al. 2018. Depression and Anxiety in Heart Failure: a Review. Harv Rev Psychiatry. 2018; 26(4): 175–18
Okwuosa I, Pumphrey D, Puthumana J, Brown R, Cotts W. Impact of identification and treatment of depression in heart transplant patients. Cardiovasc Psychiatry Neurol. 2014; 2014:747 293.
Chioncel O, et al. Epidemiology and one-year outcomes in patients with chronic heart failure and preserved, mid-range and reduced ejection fraction: an analysis of the ESC Heart Failure Long-Term Registry. Euro J Heart Fail 2017; 19(12): 1574-1585
Maggioni PA, et al. EURObservational Research Programme: regional differences and 1-year follow-up results of the Heart Failure Pilot Survey (ESC-HF Pilot). Eur J Heart Fail 2013; 15(7):808-817
Yancy et al. 2013 2013 ACCF/AHA Guideline for the Management of Heart Failure Journal of the American College of Cardiology 62(16):e147–239
Voors AA et al. 2016. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure European Heart Journal 37(27): 2129–2200
Wei J et al. Depressive Symptoms Are Associated with Mental Stress-Induced Myocardial Ischemia after Acute Myocardial Infarction. PLOS One 2014; 9(7): e102986.
Sadock BJ, Ahmad S, Sadock VA. 2019. Classification in psychiatry in Kaplan & Sadock’s pocket handbook of clinical psychiatry 6th edition. Philadelphia: Lippincott Williams & Wilkins.
Rihmer Z and Merikangas KR. 2017. Mood disorders Epidemiology in Kaplan and Sadock's Comprehensive Textbook of Psychiatry 10th edition. Philadelphia: Lippincott Williams & Wilkins.
Khayyam-Nekouei Z et al. Psychological factors and coronary heart disease. ARYA Atherosclerosis 2013; 9(1): 102
Angermann CE et al. 2018. Effect of Escitalopram on All-Cause Mortality and Hospitalization in Patients with Heart Failure and Depression The MOOD-HF Randomized Clinical Trial. JAMA 2016; 315(24); 268.
American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. 2020. Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association. Circulation 2020; 141(9): e139-e596
Piepenburg PS et al. Symptom patterns and clinical outcomes in women versus men with systolic heart failure and depression. Clinical Research in Cardiology 2019; 108: 244–25.
Corra U. 2007. Depression Following Myocardial Infarction: Prevalence, Clinical Consequences, and Patient Management in Cardiovascular Prevention and Rehabilitation. London: Springer
Zimmerman, M., Clark, H., McGonigal, P., Harris, L., Guzman Holst, C., & Martin, J. Relationship Between the DSM-5 Anxious Distress Specifier and the Hamilton Depression Rating Scale Anxiety/Somatization Factor. The Journal of Nervous and Mental Disease 2018; 206(2), 152–154
Obeid S et al. Validation of the Hamilton Depression Rating Scale (HDRS) and sociodemographic factors associated with Lebanese depressed patients. L’Encéphale. 2018, 44(5): 397-402.
Taylor, C. J., Ordóñez-Mena, J. M., Roalfe, A. K., Lay-Flurrie, S., Jones, N. R., Marshall, T., & Hobbs, F. D. R. (2019). Trends in survival after a diagnosis of heart failure in the United Kingdom 2000-2017: population-based cohort study. The BMJ, 364, 1–10. https://doi.org/10.1136/bmj.l223
Chung, M. L., Lennie, T. A., Mudd-Martin, G., Dunbar, S. B., Pressler, S. J., & Moser, D. K. (2016). Depressive symptoms in patients with heart failure negatively affect family caregiver outcomes and quality of life. European Journal of Cardiovascular Nursing, 15(1), 30–38. https://doi.org/10.1177/1474515114535329
Williams, B. A., Doddamani, S., Troup, M. A., Mowery, A. L., Kline, C. M., Gerringer, J. A., & Faillace, R. T. (2017). Agreement between heart failure patients and providers in assessing New York Heart Association functional class. Heart and Lung: Journal of Acute and Critical Care, 46(4), 293–299. https://doi.org/10.1016/j.hrtlng.2017.05.001
American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee. 2020. Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association. Circulation 2020; 141(9): e139-e596
Piepenburg PS et al. Symptom patterns and clinical outcomes in women versus men with systolic heart failure and depression. Clinical Research in Cardiology 2019; 108: 244–25.
Corra U. 2007. Depression Following Myocardial Infarction: Prevalence, Clinical Consequences, and Patient Management in Cardiovascular Prevention and Rehabilitation. London: Springer
Obeid S et al. Validation of the Hamilton Depression Rating Scale (HDRS) and sociodemographic factors associated with Lebanese depressed patients. L’Encéphale. 2018, 44(5): 397-402.
Ceccarini M, Manzoni GM, Castelnuovo G. Assessing depression in cardiac patients: what measures should be considered? Depress Res Treat. 2014; 2014:148256.
Jeyanantham K, Kotecha D, Thanki D, Dekker R, Lane DA. Effects of cognitive behavioural therapy for depressionin heart failure patients: a systematic review and meta-analysis. Heart Failure Reviews 2017; 22:731
Rutledge, T., Reis, V. A., Linke, S. E., Greenberg, B. H., & Mills, P. J. (2006). Depression in Heart Failure. A Meta-Analytic Review of Prevalence, Intervention Effects, and Associations With Clinical Outcomes. Journal of the American College of Cardiology, 48(8), 1527–1537. https://doi.org/10.1016/j.jacc.2006.06.055
Bulloch, A. G. M., Williams, J. V. A., Lavorato, D. H., & Patten, S. B. (2017). The depression and marital status relationship is modified by both age and gender. Journal of Affective Disorders, 223(April), 65–68. https://doi.org/10.1016/j.jad.2017.06.007
Celik, E., Cay, S., Sensoy, B., Murat, S., Oksuz, F., Cankurt, T., & Mendi, M. A. (2016). Heart failure functional class associated with depression severity but not anxiety severity. Acta Cardiologica Sinica, 32(1), 55–61. https://doi.org/10.6515/ACS20150509A
Sadock BJ, Ahmad S, Sadock VA. 2019. Classification in psychiatry in Kaplan & Sadock’s pocket handbook of clinical psychiatry 6th edition. Philadelphia: Lippincott Williams & Wilkins.
Prescot E. 2016. Prognostic Factors and Risk Scores in Heart Failure in Current Approach to Heart Failure. Zurich: Switzerland
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