Weaning Failure in Mechanical Ventilation: a Literature Review
DOI:
https://doi.org/10.21776/ub.hsj.2023.004.04.2Keywords:
mechanical ventilation, weaning failure, respiratory failureAbstract
Mechanical ventilation is a method of ventilation support through positive pressure breath application. It is used in cases of ventilation and/ or oxygenation failure. Due to its related complications mechanical ventilation should be withdrawn from the patient as soon as possible, called a weaning process. The result of the weaning of mechanical ventilation determines the patient’s prognosis. Patient will go through several assessments before a weaning decision is made. Subsequently, patient will be placed on an unconstrained breathing test (SBT) to check whether the patient's respiratory muscle is equipped for accepting its work of relaxing. Weaning disappointment is characterized as disappointment on SBT or reintubation at 48 hours following extubation. Several factors related to weaning failure are increasing airflow resistance, decreasing compliance, respiratory muscle fatigue, and the patient’s underlying conditions. Techniques to conquer these variables are expected to lessen the pace of disappointment of the weaning system.
References
White GC. Classification of mechanical ventilation. In: Clinical application of mechanical ventilation. 4th ed. New York: Delmar; 2014. p. 51–2.
Chang DW. Principles of mechanical ventilation. In: Clinical application of mechanical ventilation. New York: Delmar; 2014. p. 2–21.
Chang DW, Hiers JH. Initiation of mechanical ventilation. In: Clinical application of mechanical ventilation. 4th ed. New York: Delmar; 2014. p. 212.
Markle AG. Common Complications of Mechanical Ventilation and Multimodal Prevention Strategies. University of Zagreb; 2014.
Poor H. Basics of Mechanical Ventilation. Switzerland: Springer; 2018. 11–27 p.
Chang DW, Hiers JH. Weaning from mechanical ventilation. In: Clinical application of mechanical ventilation. 4th ed. New York: Delmar; 2014. p. 516.
Sandoval-Moreno LM, DÃaz-Henao WA. Factors associated with failed weaning from mechanical ventilation in adults on ventilatory support during 48 hours or more. Colomb J Anesthesiol. 2018;46(4):300–8.
Ghiani A, Paderewska J, Sainis A, Crispin A, Walcher S, Neurohr C. Variables predicting weaning outcome in prolonged mechanically ventilated tracheotomized patients: A retrospective study. J Intensive Care. 2020;8(1):1–10.
Hickey SM, Giwa AO. Mechanical ventilation. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023. p. 1–12.
Vetrugno L, Guadagnin GM, Brussa A, Orso D, Garofalo E, Bruni A, et al. Mechanical ventilation weaning issues can be counted on the fingers of just one hand: part 1. Ultrasound J. 2020;12(1).
Papaioannou V, Pneumatikos I. Prolonged weaning from mechanical ventilation: Pathophysiology and weaning strategies, key major recommendations. In: Noninvasive Mechanical Ventilation and Difficult Weaning in Critical Care: Key Topics and Practical Approaches. 2016. p. 15–20.
Emaliyawati E, Anani ED, Prawesti A. Analysis of factors affecting the weaning of mechanical ventilation at ICU RSUD Prof. Dr. Margono Soekarjo Purwokerto. PACNJ. 2019;1(10):19–25.
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